Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838678 | 0.82 | KDM4E (0.43) | TP53LMNATDP1KDM4ETHRB | |
| SCHEMBL6833883 | 0.80 | KDM4E (0.42) | TP53LMNATDP1KDM4ETHRB | |
| SCHEMBL6838661 | 0.80 | CETP (0.42) | LMNATDP1KDM4E | |
| SCHEMBL6837673 | 0.78 | HPGDS (0.47) | TP53LMNATDP1KDM4ETHRB | |
| SCHEMBL6925924 | 0.76 | GPR119 (0.44) | TP53LMNATDP1KDM4ETHRB | |
| SCHEMBL6928550 | 0.73 | PTGER4 (0.40) | ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL6927289 | 0.71 | GBA1 (0.40) | TP53LMNATDP1KDM4ETHRB | |
| SCHEMBL6927222 | 0.70 | ACKR3 (0.45) | TP53ALDH1A1THRBMAPTSMN1; SMN2 | |
| SCHEMBL6929687 | 0.70 | KDM4E (0.39) | LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6838066 | 0.69 | BRD4 (0.43) | TP53ACP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |