Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833951 | 0.89 | PTGER4 (0.38) | PTGER4BRD4TLR7ALDH1A1TSHR | |
| SCHEMBL6929687 | 0.89 | KDM4E (0.39) | PTGER4BRD4TLR7ABCC1ALDH1A1 | |
| SCHEMBL7489095 | 0.87 | TRPV1 (0.38) | PTGER4BRD4TLR7ALDH1A1TSHR | |
| SCHEMBL6929280 | 0.87 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6834046 | 0.87 | PTGER4 (0.36) | PTGER4BRD4TLR7ALDH1A1TSHR | |
| SCHEMBL6930539 | 0.84 | TLR7 (0.41) | PTGER4BRD4TLR7ALDH1A1CYP1A2 | |
| SCHEMBL6928192 | 0.83 | HTR4 (0.42) | PTGER4TLR7ABCC1 | |
| SCHEMBL6929719 | 0.82 | PTGER4 (0.37) | PTGER4BRD4ABCC1HRH3MCHR1 | |
| SCHEMBL6928754 | 0.82 | CKS1B (0.38) | PTGER4BRD4 | |
| SCHEMBL6838066 | 0.82 | BRD4 (0.43) | PTGER4BRD4TSHRHRH3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| CN-1323307-A | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |