Ethylene Glycol

Ethylene Glycol

SCHEMBL6925942

C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCCc1cc(OC(C)=O)ccc1O.OCCO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.51
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
TSHR P16473 2/20 0.45
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
CNR2 P34972 7/20 0.45
PRSS1 P07477 1/20 0.45
ACR P10323 1/20 0.45
CNR1 P21554 1/20 0.45
PTGES O14684 2/20 0.43
TOP2A P11388 1/20 0.43
TYR P14679 2/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexaethylene Glycol SCHEMBL6925944 0.89 MEN1 (0.51) ALOX5MTNR1AMTNR1BTSHRPPARG
Ethylene Glycol SCHEMBL8013191 0.86 TYR (0.46) ALOX5MTNR1AMTNR1BTSHRCNR2
Ethylene Glycol SCHEMBL8027523 0.86 TYR (0.46) ALOX5MTNR1AMTNR1BTSHRCNR2
Ether SCHEMBL6933295 0.85 THRB (0.52) ALOX5MTNR1AMTNR1BTSHRCNR2
Hexaethylene Glycol SCHEMBL8026237 0.84 MEN1 (0.45) ALOX5MTNR1AMTNR1BTSHRPPARG
SCHEMBL11372256 0.82 TSHR (0.48) ALOX5MTNR1AMTNR1BTSHRCNR2
SCHEMBL6022639 0.82 TYR (0.64) ALOX5TSHRCNR2PRSS1ACR
SCHEMBL6518152 0.81 MTNR1A (0.50) ALOX5MTNR1AMTNR1BPRSS1ACR
SCHEMBL23714926 0.79 ALOX5 (0.60) ALOX5MTNR1AMTNR1BTSHRPPARG
SCHEMBL23306718 0.79 ALOX5 (0.60) ALOX5MTNR1AMTNR1BTSHRPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801117-B1 Antifouling resin composition NIPPON PAINT CO LTD (JP) 2003-11-26 EP disclosed
US-6123755-A DOES NOT ELUTE ANTIFOULING COMPOUNDS, DURABLE NIPPON PAINT CO., LTD. (JP) 2000-09-26 US disclosed
EP-0801117-A2 Antifouling resin composition Nippon Paint Co., Ltd. (JP) 1997-10-15 EP disclosed