Hexaethylene Glycol

Hexaethylene Glycol

SCHEMBL8026237

C=CC(=O)O.CCCCCCCCCc1cc(OC(C)=O)ccc1O.OCCOCCOCCOCCOCCOCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
CASP1 P29466 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLCO1B3 Q9NPD5 1/20 0.45
SLCO1B1 Q9Y6L6 1/20 0.45
ALOX5 P09917 2/20 0.42
THRB P10828 2/20 0.41
THRA P10827 1/20 0.41
CNR2 P34972 7/20 0.40
CNR1 P21554 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
TSHR P16473 1/20 0.40
MTNR1A P48039 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexaethylene Glycol SCHEMBL6925944 0.92 MEN1 (0.51) MEN1USP2ALDH1A1LMNACYP3A4
Ethylene Glycol SCHEMBL6925942 0.84 ALOX5 (0.51) MEN1CYP3A4KMT2AALOX5CNR2
Hexaethylene Glycol SCHEMBL6931753 0.84 ALDH1A1 (0.46) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL6925947 0.83 MEN1 (0.48) MEN1USP2ALDH1A1LMNACYP3A4
Tetraethylene Glycol SCHEMBL183156 0.82 THRA (0.51) MEN1USP2ALDH1A1LMNACYP3A4
Ether SCHEMBL6933295 0.80 THRB (0.52) MEN1CYP3A4KMT2AALOX5THRB
SCHEMBL8027527 0.80 MEN1 (0.65) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL8013195 0.80 MEN1 (0.65) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL6933298 0.78 THRB (0.46) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL6931748 0.74 ADRB2 (0.41) MEN1USP2ALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6123755-A DOES NOT ELUTE ANTIFOULING COMPOUNDS, DURABLE NIPPON PAINT CO., LTD. (JP) 2000-09-26 US disclosed