Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928315 | 0.79 | MAPT (0.39) | PSMB8TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1851438 | 0.75 | PSMB8 (0.59) | PSMB8TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL18791158 | 0.73 | PSMB8 (0.58) | PSMB8TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL10473305 | 0.72 | CA2 (0.56) | PSMB8TDP1KMT2AALOX5LMNA | |
| SCHEMBL3391827 | 0.72 | PSMB8 (0.56) | PSMB8TDP1ALDH1A1ALOX5PARP1 | |
| SCHEMBL2749435 | 0.72 | PSMB8 (0.56) | PSMB8TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9676001 | 0.72 | PSMB8 (0.56) | PSMB8TDP1ALDH1A1ALOX5HDAC3 | |
| SCHEMBL25425575 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL221982 | 0.69 | PSMB8 (0.53) | PSMB8TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29954323 | 0.69 | PSMB8 (0.53) | PSMB8TDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |