Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926317 | 0.79 | PSMB8 (0.51) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL5260809 | 0.75 | ASH1L (0.46) | MAPTKDM4EHSD17B10HIF1ANPC1 | |
| SCHEMBL20969721 | 0.72 | KDM4E (0.42) | MAPTKDM4EHSD17B10HIF1ANPC1 | |
| SCHEMBL5780532 | 0.72 | TLR8 (0.49) | MAPTKDM4EHSD17B10HIF1ANPC1 | |
| SCHEMBL29954323 | 0.69 | PSMB8 (0.53) | MAPTKDM4EHSD17B10NPC1KMT2A | |
| SCHEMBL221982 | 0.69 | PSMB8 (0.53) | MAPTKDM4EHSD17B10NPC1KMT2A | |
| SCHEMBL21063750 | 0.68 | PSMB8 (0.65) | MAPTKDM4EHSD17B10HIF1ANPC1 | |
| SCHEMBL12649170 | 0.68 | ALDH1A1 (0.45) | MAPTKDM4EHSD17B10NPC1KMT2A | |
| SCHEMBL5224200 | 0.68 | KDM4E (0.39) | MAPTKDM4EHSD17B10HIF1ANPC1 | |
| SCHEMBL27774016 | 0.67 | APP (0.60) | MAPTKDM4EHSD17B10NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |