SCHEMBL29036205

SCHEMBL29036205

O=CC1CNc2ccc(F)cc2N1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
CYP1A2 P05177 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
HTR1A P08908 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1F P30939 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6926769 0.77 CREBBP (0.34) CYP1A2MAPTCYP2C19KMT2A
SCHEMBL13496703 0.75 HTR5A (0.36) CHRNB2CHRNB4CHRNA3CHRNA4CYP1A2
SCHEMBL29070701 0.74 HTR2C (0.40) CHRNB2CHRNB4CHRNA3CHRNA4HTR1A
SCHEMBL30570960 0.74 HTR2C (0.40) CHRNB2CHRNB4CHRNA3CHRNA4HTR1A
SCHEMBL27437424 0.73 TDP1 (0.35) CHRNB2CHRNA4CYP1A2MAPTKMT2A
SCHEMBL28115423 0.73 PARP1 (0.36) CYP1A2MAPTCYP2C19KMT2AHTR1D
SCHEMBL27740237 0.73 CMA1 (0.34) CYP1A2CYP2C19KMT2A
SCHEMBL28997205 0.73 ALDH1A1 (0.34) CYP1A2MAPTKMT2A
Methylamine SCHEMBL27568812 0.72 BRD4 (0.35) CYP1A2MAPTCYP2C19KMT2A
SCHEMBL28114067 0.72 ESR1 (0.36) CYP1A2MAPTCYP2C19KMT2AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116462636-A Synthesis method of 3-alkyl quinoxaline-2 (1H) ketone compound mediated by visible light 河南师范大学 2023-07-21 CN disclosed