Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607595 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL5661855 | 0.85 | MAPT (0.72) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL6058010 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL18376679 | 0.82 | PDE7A (0.62) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL6930035 | 0.82 | PLA2G4A (0.69) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL26332304 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL13236474 | 0.80 | MAPT (0.78) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL810620 | 0.78 | PDE7A (0.62) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL6929988 | 0.77 | VCAM1 (0.61) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL8702711 | 0.77 | VCAM1 (0.74) | ALDH1A1MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| CN-1321153-A | telomerase inhibitors and methods of use thereof | GERON CORP (US) | 2001-11-07 | — | — | CN | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |