Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.49 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930035 | 0.86 | PLA2G4A (0.69) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 | |
| SCHEMBL6058010 | 0.81 | ALDH1A1 (0.60) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 | |
| SCHEMBL18376679 | 0.81 | PDE7A (0.62) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 | |
| SCHEMBL5661855 | 0.81 | MAPT (0.72) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 | |
| SCHEMBL560001 | 0.77 | VCAM1 (1.00) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28559170 | 0.77 | MAPT (0.68) | ALDH1A1PLA2G4AMAPTMEN1KMT2A | |
| SCHEMBL27607595 | 0.77 | ALDH1A1 (0.56) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 | |
| SCHEMBL6927148 | 0.77 | ALDH1A1 (0.60) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 | |
| SCHEMBL20535359 | 0.77 | ALDH1A1 (0.53) | VCAM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6512918 | 0.76 | ALDH5A1 (0.61) | VCAM1ALDH1A1PLA2G4AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638909-A | Compounds with antibacterial activity | 香港理工大学 | 2021-04-09 | — | — | CN | disclosed |
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |