Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 8/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927980 | 0.87 | HTR2C (0.57) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| SCHEMBL7526768 | 0.83 | SLC6A4 (0.56) | SLC6A4HTR1ASLC6A2SLC6A3GBA1 | |
| SCHEMBL6927951 | 0.83 | SLC6A4 (0.63) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| SCHEMBL16657602 | 0.81 | FPR2 (0.52) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL28086978 | 0.80 | FPR2 (0.51) | SLC6A4SLC6A2SLC6A3HTR2CHTR2A | |
| SCHEMBL6929202 | 0.79 | HTR2C (0.52) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| SCHEMBL30933777 | 0.77 | PRMT5 (0.46) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL30933829 | 0.76 | PRMT5 (0.45) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| SCHEMBL6927769 | 0.76 | SLC6A4 (0.56) | SLC6A4HTR1ASLC6A2SLC6A3HTR2C | |
| SCHEMBL6925382 | 0.76 | SLC6A4 (0.48) | SLC6A4HTR1ASLC6A2SLC6A3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518284-B2 | For inhibiting the serotonin and/or noradrenaline reuptake, and are useful as medicaments in disorders in which an increase of levels of those neurotransmitters is necessary | FAES, FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS S.A. (ES) | 2003-02-11 | — | — | US | claimed |
| US-20020038031-A1 | New 4 - substituted piperidines | ORJALES VENERO AURELIO (ES) | 2002-03-28 | — | — | US | claimed |
| EP-1002794-A1 | 4-[(Aryl)(aryloxy)methyl]piperidine derivatives and their use as serotonin and/or noradrenaline reuptake inhibitors | FAES, Fabrica Espanola de Productos Quimicos y Farmaceuticos, S.A. (ES) | 2000-05-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038031-A1 | New 4 - substituted piperidines | ADRA2C, ADRB2, ADRB1 | SLC6A4 11/4885HTR1A 16/4885SLC6A2 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.