SCHEMBL6927683

SCHEMBL6927683

Clc1nc2ccccc2c2c1nc(-c1cccs1)n2CCC1CCNCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 2/20 0.40
KDM4E B2RXH2 10/20 0.38
ALDH1A1 P00352 9/20 0.38
HPGD P15428 8/20 0.38
HSD17B10 Q99714 5/20 0.38
GLA P06280 3/20 0.38
LMNA P02545 2/20 0.38
USP2 O75604 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 3/20 0.38
MAPT P10636 5/20 0.37
TP53 P04637 2/20 0.37
ACP1 P24666 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
POLB P06746 2/20 0.36
HTT P42858 1/20 0.36
RCE1 Q9Y256 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6929021 0.90 KDM4E (0.40) NPY1RKDM4EALDH1A1HPGDHSD17B10
SCHEMBL6840109 0.87 KDM4E (0.38) NPY1RKDM4EALDH1A1HPGDHSD17B10
SCHEMBL6923309 0.87 NPY1R (0.40) NPY1RKDM4EACP1POLBHTR6
SCHEMBL6925914 0.86 NPY1R (0.44) NPY1RALDH1A1LMNAACP1SMN1; SMN2
Hydrochloric Acid SCHEMBL6923145 0.85 NPY1R (0.43) NPY1RACP1HTR6HTR4MAOB
SCHEMBL6927043 0.85 NPY1R (0.41) NPY1RACP1HTR6HTR4MAOB
SCHEMBL6926022 0.85 NPY1R (0.39) NPY1RACP1HTR6HTR4MAOB
SCHEMBL6833774 0.84 PLAUR (0.39) NPY1RKDM4EALDH1A1HPGDLMNA
SCHEMBL6922923 0.83 NPY1R (0.41) NPY1RALDH1A1ACP1MEN1KMT2A
SCHEMBL6929042 0.82 NPY1R (0.40) NPY1RACP1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed