SCHEMBL6833774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6838078	0.88	MERTK (0.43)	MERTKACP1NPY1RALDH1A1HTR4
	SCHEMBL6929021	0.85	KDM4E (0.40)	PLAURACP1NPY1RCYP2C9LMNA
	SCHEMBL6927683	0.84	NPY1R (0.40)	PLAURACP1NPY1RCYP2C9LMNA
	SCHEMBL6840109	0.83	KDM4E (0.38)	PLAURACP1NPY1RCYP2C9LMNA
	SCHEMBL7489996	0.82	NPY1R (0.40)	MERTKACP1NPY1RALDH1A1TSHR
	SCHEMBL6928192	0.82	HTR4 (0.42)	MERTKACP1NPY1RHTR4PDE6D
	SCHEMBL6838688	0.81	ALDH1A1 (0.38)	MERTKNPY1RLMNAMEN1ALDH1A1
	SCHEMBL6929281	0.81	NPY1R (0.40)	MERTKACP1HDAC1NPY1RHTR4
	SCHEMBL6925914	0.81	NPY1R (0.44)	MERTKACP1NPY1RLMNAALDH1A1
	SCHEMBL6838557	0.81	MAOB (0.39)	MERTKACP1NPY1RHTR4PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.