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SCHEMBL6927043

SCHEMBL6927043

Clc1nc2ccccc2c2c1nc(-c1nccs1)n2CCC1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 4/20 0.41
▸ HTR4 Q13639 1/20 0.37
▸ MERTK Q12866 1/20 0.35
▸ MAOB P27338 6/20 0.34
▸ HTR6 P50406 6/20 0.34
▸ ACP1 P24666 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6924606 0.90 HTR4 (0.39) NPY1RHTR4MERTKACP1
SCHEMBL6838657 0.88 NPY1R (0.36) NPY1RHTR4MERTKACP1
SCHEMBL6926022 0.85 NPY1R (0.39) NPY1RHTR4MERTKMAOBHTR6
SCHEMBL6927683 0.85 NPY1R (0.40) NPY1RHTR4MAOBHTR6ACP1
SCHEMBL6925914 0.85 NPY1R (0.44) NPY1RHTR4MERTKMAOBHTR6
Hydrochloric Acid SCHEMBL6923145 0.84 NPY1R (0.43) NPY1RHTR4MERTKMAOBHTR6
SCHEMBL6925994 0.83 NPY1R (0.42) NPY1RHTR4MERTKMAOBHTR6
SCHEMBL6923309 0.81 NPY1R (0.40) NPY1RHTR4MERTKMAOBHTR6
SCHEMBL6922923 0.81 NPY1R (0.41) NPY1RHTR4MERTKMAOBHTR6
SCHEMBL6929551 0.80 PDE6D (0.41) NPY1RHTR4MAOBHTR6ACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 — — US disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 — — EP disclosed