SCHEMBL6927705 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	HSD11B1	P28845	14/20	0.45

▸	HSD17B1	P14061	2/20	0.45

▸	HSD17B2	P37059	2/20	0.45

▸	HTT	P42858	1/20	0.40

▸	EDNRB	P24530	2/20	0.39

▸	EDNRA	P25101	2/20	0.39

▸	SLC40A1	Q9NP59	1/20	0.37

▸	ALDH1A1	P00352	1/20	0.36

▸	HSD17B10	Q99714	1/20	0.36

▸	CCR4	P51679	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7059009	0.87	HSD11B1 (0.47)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5832114	0.79	HSD11B1 (0.48)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5409824	0.78	HSD11B1 (0.51)	HSD11B1HSD17B1HSD17B2EDNRBEDNRA
SCHEMBL6927700	0.78	HSD11B1 (0.48)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5831160	0.78	HSD11B1 (0.46)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5831410	0.77	HSD11B1 (0.51)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL6624383	0.77	HSD11B1 (0.55)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5389806	0.76	ALDH1A1 (0.47)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5389813	0.76	ALDH1A1 (0.47)	HSD11B1HSD17B1HSD17B2HTTEDNRB
SCHEMBL5832066	0.75	HSD11B1 (0.50)	HSD11B1HSD17B1HSD17B2HTTEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004113310-A1	USE OF AN INHIBITOR OF 11-B-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPOUNDS FOR PROMOTING WOUND HEALING	BIOVITRUM AB (SE)	2004-12-29	—	—	WO	disclosed