Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.39 |
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1152627 | 0.81 | TAS1R3 (0.44) | TAS1R3TAS1R1POLBTSHRCA1 | |
| SCHEMBL8022828 | 0.80 | TP53 (0.39) | TAS1R3TAS1R1POLBKDM4EMEN1 | |
| SCHEMBL8708085 | 0.78 | POLB (0.40) | TAS1R3TAS1R1POLBTSHRCA1 | |
| SCHEMBL2687043 | 0.76 | TAS1R3 (0.36) | TAS1R3TAS1R1POLBTSHRCA1 | |
| SCHEMBL6928309 | 0.75 | ALDH1A1 (0.49) | TAS1R3TAS1R1POLBTSHRKDM4E | |
| SCHEMBL8703906 | 0.75 | POLB (0.39) | POLBCA1CA2CA9CA12 | |
| SCHEMBL812203 | 0.75 | ATM (0.41) | TAS1R3TAS1R1KDM4EMEN1KMT2A | |
| SCHEMBL5733102 | 0.74 | KMT2A (0.40) | TAS1R3TAS1R1POLBTSHRKDM4E | |
| SCHEMBL1812603 | 0.74 | SMN1; SMN2 (0.42) | TAS1R3TAS1R1POLBTSHRKDM4E | |
| SCHEMBL24841250 | 0.72 | CYP3A4 (0.46) | POLBKDM4EMEN1KMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-7947704-B2 | 2,4,6-phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-05-24 | — | — | US | disclosed |
| US-7947704-B2 | 2,4,6-phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-05-24 | — | — | US | disclosed |
| US-7947704-B2 | 2,4,6-phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-05-24 | — | — | US | disclosed |
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1732930-A2 | 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092897-A2 | 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES | BAYER CROPSCIENCE AG (DE) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | TAS1R3 4459/4885TAS1R1 4551/4885POLB 3290/4885 |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | TAS1R3 4459/4885TAS1R1 4551/4885POLB 3290/4885 |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | CYP4X1, KDM4E, KCNE1 | TAS1R3 4495/4885TAS1R1 4588/4885POLB 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.