SCHEMBL69285

SCHEMBL69285

CC1(C)c2ccc(Br)cc2-c2nc(Cl)ccc21

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 2/20 0.32
KMT2A Q03164 2/20 0.32
RAB9A P51151 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
PDE4B Q07343 1/20 0.32
NT5E P21589 1/20 0.30
IDO1 P14902 1/20 0.30
GPR35 Q9HC97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29926719 1.00 MEN1 (0.32) MEN1MAPTHTTKMT2ARAB9A
SCHEMBL12127091 0.78 TDP2 (0.41) TDP2NSD2
SCHEMBL68562 0.78 PGR (0.36) KMT2ATDP2NSD2
SCHEMBL805016 0.76 S100A4 (0.41) MEN1MAPTKMT2ATDP2PDE4B
SCHEMBL30567840 0.76 S100A4 (0.41) MEN1MAPTKMT2ATDP2PDE4B
SCHEMBL2512872 0.76 RAB9A (0.39) MEN1MAPTHTTKMT2ARAB9A
SCHEMBL17886472 0.75 CCR1 (0.32) TDP2NSD2
SCHEMBL70585 0.74 PDK2 (0.39) MEN1MAPTHTTKMT2ARAB9A
SCHEMBL24731040 0.74 PDK2 (0.38) MEN1MAPTHTTKMT2A
SCHEMBL69252 0.72 PDE4B (0.37) MEN1MAPTHTTKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234106-B Four-tooth ring metal complex and organic light-emitting device 北京八亿时空液晶科技股份有限公司 2022-11-04 CN disclosed
CN-113234106-A Four-tooth ring metal complex and organic light-emitting device 北京八亿时空液晶科技股份有限公司 2021-08-10 CN disclosed
US-8129899-B1 Azafluorene derivative and organic light-emitting device using the derivative CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
US-20120049176-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 2012-03-01 US disclosed
US-8110685-B2 Efficient, durable electron transport layers; low driving voltage; simple, low cost production CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-20080154040-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154040-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE AZI2, CYP1A2, CYP2C19 MEN1 1980/4885MAPT 3499/4885HTT 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.