SCHEMBL692866

SCHEMBL692866

Clc1cccc2cccnc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.61
TSHR P16473 2/20 0.61
CCR1 P32246 2/20 0.61
CCR8 P51685 2/20 0.61
KDM4E B2RXH2 2/20 0.61
LMNA P02545 2/20 0.61
GMNN O75496 1/20 0.61
TP53 P04637 1/20 0.61
HSP90AA1 P07900 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2D6 P10635 1/20 0.61
MAPT P10636 1/20 0.61
MMP9 P14780 1/20 0.61
ALOX15 P16050 1/20 0.61
NFKB1 P19838 1/20 0.61
MMP8 P22894 1/20 0.61
THPO P40225 1/20 0.61
MTOR P42345 1/20 0.61
HTT P42858 1/20 0.61
MMP13 P45452 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358836 1.00 MMP2 (0.61) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL10938107 0.98 MMP2 (0.58) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL4461988 0.98 MMP2 (0.58) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL5325898 0.83 LMNA (0.58) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL29241785 0.83 LMNA (0.52) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL31175945 0.83 LMNA (0.58) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL28129964 0.81 TSHR (0.56) MMP2TSHRCCR1CCR8KDM4E
SCHEMBL22963304 0.80 ALDH1A1 (0.66) MMP2TSHRCCR1CCR8KDM4E
Phenanthroline SCHEMBL29367277 0.76 CCR1 (1.00) MMP2TSHRCCR1CCR8KDM4E
Phenanthroline SCHEMBL8312 0.76 CCR1 (1.00) MMP2TSHRCCR1CCR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 926 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119702019-A Catalyst for catalyzing selective hydrogenation of quinoline and preparation method thereof 湘潭大学 2025-03-28 CN claimed
CN-114164491-A Ion-doped gadolinium-gallium garnet crystal and preparation method and application thereof 山东大学 2022-03-11 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-105753838-A Novel high-regioselectivity amination method of quinoline derivatives 安阳师范学院 2016-07-13 CN claimed
CN-103604791-A Fluorescence spectroscopic method for measuring azides ions UNIV GUANGXI NORMAL 2014-02-26 CN claimed
US-7981578-B2 Additive containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-20090246660-A1 ADDITIVE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
CN-1914173-A Quinolines useful in treating cardiovascular disease WYETH CORP (US) 2007-02-14 CN claimed
CN-1067380-C Method for conversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines AMERICAN CYANAMID CO (US) 2001-06-20 CN claimed
EP-0744399-B1 Conversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines AMERICAN CYANAMID CO (US) 2000-10-25 EP claimed
EP-0505890-B1 Process for producing a styrenic polymer IDEMITSU KOSAN CO (JP) 1997-05-28 EP claimed
CN-1146989-A Method for conversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines AMERICAN CYANAMID CO (US) 1997-04-09 CN claimed
US-5597924-A Coversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines AMERICAN CYANAMID COMPANY (US) 1997-01-28 US claimed
EP-0744399-A2 Conversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines American Cyanamid Company (US) 1996-11-27 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4496727-A ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS CIBA-GEIGY CORPORATION (US) 1985-01-29 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR MMP2 4517/4885TSHR 3267/4885CCR1 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.