Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 9/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11150638 | 0.84 | OPRM1 (0.53) | OPRM1HTR2ATACR1AKT2HRH1 | |
| SCHEMBL6928751 | 0.72 | OPRM1 (0.40) | OPRM1HTR2ATACR1 | |
| SCHEMBL10605630 | 0.71 | DRD3 (0.37) | OPRM1SLC6A4 | |
| SCHEMBL7342703 | 0.71 | TACR1 (0.52) | OPRM1TACR1SLC6A4KCNH2 | |
| SCHEMBL10515881 | 0.70 | TACR1 (0.52) | TACR1SLC6A4KCNH2 | |
| SCHEMBL6932312 | 0.70 | OPRM1 (0.42) | OPRM1TACR1 | |
| SCHEMBL10424968 | 0.69 | OPRM1 (0.47) | OPRM1HTR2ATACR1AKT2TSHR | |
| SCHEMBL613551 | 0.69 | OPRM1 (0.55) | OPRM1HTR2ATACR1AKT2TSHR | |
| SCHEMBL10514596 | 0.69 | ALDH1A1 (0.41) | OPRM1 | |
| SCHEMBL8166976 | 0.69 | OPRM1 (0.55) | OPRM1HTR2ATACR1AKT2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366066-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072621-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-19 | — | — | WO | disclosed |