Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212375 | 0.96 | TSHR (0.35) | ALDH1A1TSHRSMN1; SMN2CNR1LMNA | |
| SCHEMBL212374 | 0.96 | TSHR (0.35) | ALDH1A1TSHRSMN1; SMN2CNR1LMNA | |
| SCHEMBL2903107 | 0.96 | TSHR (0.35) | ALDH1A1TSHRSMN1; SMN2CNR1LMNA | |
| SCHEMBL1009436 | 0.89 | — | — | |
| SCHEMBL1009437 | 0.89 | — | — | |
| SCHEMBL24541143 | 0.86 | LMNA (0.40) | ALDH1A1TSHRTOP1CNR1LMNA | |
| SCHEMBL887929 | 0.86 | LMNA (0.40) | ALDH1A1TSHRCNR1LMNAHSD17B10 | |
| SCHEMBL164212 | 0.86 | — | — | |
| SCHEMBL25311340 | 0.86 | — | — | |
| SCHEMBL1010143 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515154-B2 | Acetoacetic acid derivatives, process for their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
| US-20010056195-A1 | Acetoacetic acid derivatives, process for their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056195-A1 | Acetoacetic acid derivatives, process for their preparation and their use | ACMSD, MLYCD, HADHB | ALDH1A1 20/4885TSHR 3368/4885TOP1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.