Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713502 | 0.85 | TAS1R3 (0.36) | HPGDKMT2AKDM4EGAA | |
| SCHEMBL8015573 | 0.82 | TAS1R3 (0.33) | HPGDCYP3A4KDM4EGAA | |
| SCHEMBL13527178 | 0.81 | — | — | |
| SCHEMBL13002854 | 0.79 | EZH2 (0.30) | — | |
| SCHEMBL10309266 | 0.78 | HTR2A (0.39) | — | |
| SCHEMBL13002674 | 0.78 | ALDH1A1 (0.33) | CYP3A4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10199715 | 0.75 | TAS1R3 (0.32) | HPGDALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL12270006 | 0.75 | PPOX (0.40) | ALDH1A1GAASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL9883891 | 0.74 | HTR2A (0.36) | — | |
| SCHEMBL10257698 | 0.74 | KDM4E (0.33) | HPGDCYP3A4ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569810-B1 | (2-alkoxycarbonylcyclohexyl) (substituted benzyl) ketones of given formula; insecticidal, acaricidal and herbicidal action | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-27 | — | — | US | disclosed |
| US-6515184-B1 | The present invention relates to novel bicyclic cyclopentane-1,3- dione derivatives of the formula (I) to a process for their preparation and to their use as pesticides and herbicides. | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
| EP-0854852-B1 | CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0854852-A1 | CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997014667-A1 | CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-24 | — | — | WO | disclosed |