SCHEMBL692926

SCHEMBL692926

CCCC1Oc2ccccc2O1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
POLB P06746 1/20 0.39
ESR2 Q92731 1/20 0.39
PARP1 P09874 2/20 0.38
HPGD P15428 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
PLA2G6 O60733 2/20 0.38
PLA2G4A P47712 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HTT P42858 1/20 0.37
USP2 O75604 1/20 0.35
MTNR1A P48039 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618689 0.86 HPGD (0.43) CA2POLBESR2PARP1HPGD
SCHEMBL27816269 0.85 GRM2 (0.44) CA2HPGDKMT2AMEN1ALDH1A1
SCHEMBL15111194 0.83 GRM2 (0.45) HPGDCYP1A2KMT2AMEN1ALDH1A1
SCHEMBL3763119 0.80 CA2 (0.45) CA2POLBESR2PARP1HPGD
SCHEMBL2475144 0.77 PLA2G6 (0.36) ESR2CYP1A2CYP2C19PLA2G6PLA2G4A
SCHEMBL407486 0.76 CA2 (0.47) CA2PARP1HTT
SCHEMBL1689230 0.76 CA2 (0.42) CA2POLBPARP1SMN1; SMN2HTT
SCHEMBL8098626 0.76 CA2 (0.42) CA2POLBPARP1KMT2AMEN1
SCHEMBL6272291 0.76 CA2 (0.42) CA2POLBPARP1HPGDSMN1; SMN2
SCHEMBL17818421 0.76 ESR1 (0.47) ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9364511-B2 Antiviral preparations obtained from a natural cinnamon extract RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-06-14 US disclosed
EP-1711192-B1 ANTIVIRAL PREPARATIONS OBTAINED FROM A NATURAL CINNAMON EXTRACT UNIV RAMOT (IL) 2013-12-04 EP disclosed
EP-2422805-A1 Antiviral preparations obtained from a natural cinnamon extract Ramot at Tel-Aviv University Ltd. (IL) 2012-02-29 EP disclosed
CN-1897958-B Antiviral preparations obtained from a natural cinnamon extract UNIV RAMOT 2011-02-02 CN disclosed
US-20090209605-A1 NEMATICIDAL COMPOSITIONS DEVGEN N.V. (BE) 2009-08-20 US disclosed
US-7390804-B2 N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-24 US disclosed
US-7390804-B2 N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-06-24 US disclosed
US-20080146445-A1 Nematicidal Compositions DEVGEN NV (BE) 2008-06-19 US disclosed
CN-1897958-A Antiviral preparations obtained from a natural cinnamon extract UNIV RAMOT (IL) 2007-01-17 CN disclosed
US-20060275515-A1 Antiviral preparations obtained from a natural cinnamon extract RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2006-12-07 US disclosed
EP-1165557-A1 ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS NEUROGEN CORPORATION (US) 2002-01-02 EP disclosed
WO-2000059905-A1 ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS NEUROGEN CORPORATION (US) 2000-10-12 WO disclosed
US-4540800-A FROM CATECHOL, ALDEHYDE OR ALLYL ALCOHOL, SOLID ACID CATALYST UBE INDUSTRIES, LTD. (JP) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209605-A1 NEMATICIDAL COMPOSITIONS ACHE, DNPH1, NANP CA2 3555/4885POLB 3743/4885ESR2 4630/4885
US-20080146445-A1 Nematicidal Compositions ACHE, DNPH1, NANP CA2 3555/4885POLB 3743/4885ESR2 4630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.