SCHEMBL6929280

SCHEMBL6929280

CN1CCN(c2nc3ccccc3c3c2nc(-c2ccccc2)n3CCC2CCN(C(=O)O)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928550 0.87 PTGER4 (0.40) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL6833951 0.84 PTGER4 (0.38) ALDH1A1
SCHEMBL6929687 0.84 KDM4E (0.39) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL7489095 0.83 TRPV1 (0.38) ALDH1A1
SCHEMBL6834046 0.82 PTGER4 (0.36) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL6930539 0.79 TLR7 (0.41) KDM4EALDH1A1HSD17B10
SCHEMBL6928754 0.78 CKS1B (0.38)
SCHEMBL6929719 0.78 PTGER4 (0.37)
SCHEMBL6838066 0.78 BRD4 (0.43) HSD17B10
SCHEMBL6838678 0.76 KDM4E (0.43) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518265-B1 1H-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2003-02-11 US disclosed
CN-1323307-A 1H-imidazopyridine derivatives HOKURIKU SEIYAKU (JP) 2001-11-21 CN disclosed
EP-1104764-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2001-06-06 EP disclosed