Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838066 | 0.93 | BRD4 (0.43) | TRPV1PTGER4HRH3TSHRBRD4 | |
| SCHEMBL6833883 | 0.89 | KDM4E (0.42) | CKS1BSKP1SKP2TP53 | |
| SCHEMBL6928550 | 0.87 | PTGER4 (0.40) | PTGER4HRH3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6833951 | 0.87 | PTGER4 (0.38) | PTGER4HRH3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6837624 | 0.85 | ACHE (0.47) | — | |
| SCHEMBL6833713 | 0.84 | NPY1R (0.39) | TLR7 | |
| SCHEMBL6929687 | 0.84 | KDM4E (0.39) | PTGER4HRH3ALDH1A1TSHRTLR7 | |
| SCHEMBL6834046 | 0.84 | PTGER4 (0.36) | PTGER4HRH3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6840051 | 0.83 | P2RX3 (0.34) | PTGER4TSHRSMN1; SMN2BRD4 | |
| SCHEMBL6929280 | 0.83 | KDM4E (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |