Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 4/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838661 | 0.89 | CETP (0.42) | KDM4E | |
| SCHEMBL6928550 | 0.87 | PTGER4 (0.40) | PTGER4BRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6833951 | 0.86 | PTGER4 (0.38) | PTGER4BRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6833690 | 0.85 | HTR4 (0.39) | TLR7CTSSCTSK | |
| SCHEMBL7489095 | 0.84 | TRPV1 (0.38) | PTGER4BRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6929687 | 0.83 | KDM4E (0.39) | PTGER4BRD4ALDH1A1TSHRKDM4E | |
| SCHEMBL6929280 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6930539 | 0.81 | TLR7 (0.41) | PTGER4BRD4ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6929719 | 0.77 | PTGER4 (0.37) | PTGER4BRD4HRH3IDO1 | |
| SCHEMBL6928754 | 0.77 | CKS1B (0.38) | PTGER4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | PTGER4 1430/4885BRD4 212/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.