Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.59 |
| ▸ | F10 | P00742 | 7/20 | 0.50 |
| ▸ | PLAT | P00750 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931908 | 0.83 | F2 (0.56) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL6930600 | 0.75 | F2 (1.00) | F2F10PLATPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6929471 | 0.75 | F2 (0.98) | F2F10PLATPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6929473 | 0.70 | F2 (0.55) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL5330184 | 0.69 | ALDH1A1 (0.58) | F2ALDH1A1NPSR1KMT2AKDM4E | |
| SCHEMBL30084182 | 0.69 | ALDH1A1 (0.58) | F2ALDH1A1NPSR1KMT2AKDM4E | |
| SCHEMBL4927896 | 0.68 | ALDH1A1 (0.53) | F2ALDH1A1NPSR1KMT2AKDM4E | |
| SCHEMBL6929890 | 0.68 | F2 (1.00) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL29236645 | 0.67 | LOXL2 (0.40) | ALDH1A1KMT2AKDM4EMEN1TP53 | |
| SCHEMBL16144650 | 0.67 | ALDH1A1 (0.54) | F2ALDH1A1NPSR1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225131-A1 | Thrombin inhibitors | BURGEY CHRISTOPHER S (US) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225131-A1 | Thrombin inhibitors | TFPI, SERPINC1, PLAT | F2 5/4885F10 27/4885PLAT 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.