Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994752 | 0.88 | SRR (0.47) | KMT2ANPC1RAB9ACTRB1SRR | |
| SCHEMBL7747380 | 0.86 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTKMT2ANPC1 | |
| SCHEMBL7747823 | 0.86 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTKMT2ANPC1 | |
| SCHEMBL8024394 | 0.86 | SLC7A5 (0.54) | ALDH1A1POLBMAPTKMT2ANPC1 | |
| SCHEMBL27441072 | 0.84 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTKMT2ANPC1 | |
| SCHEMBL8583257 | 0.84 | ALPI (0.47) | ALDH1A1NPC1RAB9ACTRB1TACR1 | |
| SCHEMBL11680719 | 0.79 | HPGD (0.58) | ALDH1A1POLBKMT2ANPC1RAB9A | |
| SCHEMBL3425339 | 0.78 | ATM (0.51) | CTSLACE | |
| SCHEMBL979240 | 0.78 | KMT2A (0.55) | ALDH1A1POLBMAPTKMT2ANPC1 | |
| SCHEMBL180159 | 0.78 | KMT2A (0.55) | ALDH1A1POLBMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368328-A1 | METHODS FOR PREPARING NEW TAXOIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2003-12-10 | — | — | EP | claimed |
| WO-2002070498-A1 | METHODS FOR PREPARING NEW TAXOIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA, S.A. (FR) | 2002-09-12 | — | — | WO | claimed |