SCHEMBL5994752

SCHEMBL5994752

O=C(O)NOC(=O)C(O)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 2/20 0.47
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
MMP8 P22894 1/20 0.46
CYP1A2 P05177 1/20 0.46
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
EPHX1 P07099 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
LTA4H P09960 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CTRB1 P17538 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8583257 0.88 ALPI (0.47) SRRALPIPKMPTGS1XIAP
SCHEMBL6929828 0.88 ALDH1A1 (0.54) SRRALPIPKMPTGS1XIAP
SCHEMBL3425339 0.82 ATM (0.51)
SCHEMBL2336410 0.81 SRR (0.55) SRRALPIPKMPTGS1XIAP
SCHEMBL180159 0.81 KMT2A (0.55) MMP8CYP1A2NPC1RAB9ALTA4H
SCHEMBL3980617 0.81 KMT2A (0.55) MMP8CYP1A2NPC1RAB9ALTA4H
SCHEMBL979240 0.81 KMT2A (0.55) MMP8CYP1A2NPC1RAB9ALTA4H
SCHEMBL28260760 0.81 EPHX1 (0.46) SRRALPIPKMPTGS1XIAP
Water SCHEMBL27509393 0.81 CTSS (0.51)
SCHEMBL6284464 0.80 MMP8 (0.59) PKMMMP8CYP1A2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1694660-A1 PROCESS FOR THE PREPARATION OF ANHYDROUS AND HYDRATED ACTIVE PHARMACEUTICAL INGREDIENTS (APIS); STABLE PHARMACEUTICAL COMPOSITIONS PREPARED FROM THE SAME AND USES OF SAID COMPOSITIONS Quiral Quimica Do Brasil (BR) 2006-08-30 EP disclosed
WO-2005061474-A1 PROCESS FOR THE PREPARATION OF ANHYDROUS AND HYDRATED ACTIVE PHARMACEUTICAL INGREDIENTS (APIS); STABLE PHARMACEUTICAL COMPOSITIONS PREPARED FROM THE SAME AND USES OF SAID COMPOSITIONS QUIRAL QUÍMICA DO BRASIL (BR) 2005-07-07 WO disclosed