Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747380 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL6929828 | 0.86 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL7747796 | 0.84 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL8024394 | 0.76 | SLC7A5 (0.54) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL8794289 | 0.75 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL27441072 | 0.75 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL5994752 | 0.74 | SRR (0.47) | NPC1RAB9AKMT2ACTRB1 | |
| SCHEMBL11680719 | 0.72 | HPGD (0.58) | ALDH1A1NPC1RAB9APOLBKMT2A | |
| SCHEMBL27468751 | 0.71 | KMT2A (0.59) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL8583257 | 0.71 | ALPI (0.47) | ALDH1A1NPC1RAB9ALMNACTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116718-A2 | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-07-18 | — | — | EP | disclosed |
| EP-0776322-A1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-06-04 | — | — | EP | disclosed |
| WO-1997000870-A1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-01-09 | — | — | WO | disclosed |