SCHEMBL6930099

SCHEMBL6930099

COC(=O)C(=Cc1ccc(N)cc1)C(=O)OC

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
HPGD P15428 1/20 0.49
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
LMNA P02545 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
S1PR4 O95977 1/20 0.45
S1PR1 P21453 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14433039 0.91 TP53 (0.44) MAPTHPGDMEN1KMT2A
SCHEMBL13552273 0.90 MAPT (0.56) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL1259194 0.83 CYP19A1 (0.42) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL1259189 0.83 CYP19A1 (0.42) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL8138421 0.82 MAPT (0.50) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL3519645 0.82 KDM4E (0.62) MAPTHPGD
SCHEMBL77732 0.82 MEN1 (0.63) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL5142723 0.81 MAPK1 (0.47) MAPTHPGDMEN1KMT2ANPSR1
SCHEMBL2414235 0.81 MAPT (0.49) MAPTHPGDCYP2C9
SCHEMBL3921874 0.81 MAPT (0.67) MAPTHPGDMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9573887-B2 Naphthalene derivative DAITO CHEMIX CORPORATION (JP) 2017-02-21 US disclosed
EP-2599771-B1 NAPHTHALENE DERIVATIVE DAITO CHEMIX CORP (JP) 2016-09-14 EP disclosed
US-20130184241-A1 Naphthalene Derivative KYOTO UNIVERSITY (JP) 2013-07-18 US disclosed
EP-2599771-A1 NAPHTHALENE DERIVATIVE Daito Chemix Corporation (JP) 2013-06-05 EP disclosed
EP-1568700-B1 S-triazine derivatives containing at least two silated p-aminobenzalmalonate groups, sunscreen compositions containing these derivatives as well as the use of the derivatives OREAL (FR) 2007-08-08 EP disclosed
US-6517742-B1 2-(butyl 4'-ylaminobenzoate)-4,6-bis((1,3,3,3-tetramethyl-1 -((trimethylsilyl)oxy)disiloxanyl)propyl-3-ylamino)-s-triazine; s-triazine derivatives substituted by at least one silicone group; from cyanuric chloride L'OREAL (FR) 2003-02-11 US disclosed
US-5928630-A PROTECT AGAINST SOLAR RADIATION; ABSORB BOTH ULTRAVIOLET A AND B RADIATION Societe L' Oreal S.A. (FR) 1999-07-27 US disclosed
US-5849909-A Benzalmalonatae/phenylcyanoacrylate-substituted S-triazine compounds SOCIETE L'OREAL S.A. (FR) 1998-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130184241-A1 Naphthalene Derivative VCP, NOC2L, VAT1 MAPT 121/4885HPGD 549/4885MEN1 2693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.