Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085801 | 0.69 | DDB1 (0.51) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL2435976 | 0.68 | ELANE (0.51) | ELANEKMT2AMEN1GSK3AGSK3B | |
| SCHEMBL6934223 | 0.68 | ELANE (0.44) | ELANEKMT2AMEN1F2PLG | |
| SCHEMBL6734920 | 0.67 | GSK3A (0.47) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL6933858 | 0.67 | ELANE (0.42) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL8489655 | 0.67 | GAA (0.50) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL17328481 | 0.65 | KMT2A (0.56) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL15319579 | 0.65 | KMT2A (0.56) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL15374440 | 0.65 | KMT2A (0.56) | ELANEKMT2ADDB1CRBNMEN1 | |
| SCHEMBL10870338 | 0.63 | ELANE (0.55) | ELANEKMT2ADDB1CRBNMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |