Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933858 | 0.80 | ELANE (0.42) | ELANEALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7845423 | 0.70 | MEN1 (0.53) | ELANEALDH1A1MEN1KMT2ACTSG | |
| SCHEMBL6733172 | 0.69 | MEN1 (0.42) | ELANEALDH1A1MEN1KMT2ACTSG | |
| SCHEMBL6930362 | 0.68 | ELANE (0.42) | ELANEMEN1KMT2ACTSGCYP2C19 | |
| SCHEMBL6934334 | 0.66 | LMNA (0.40) | ELANEALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6728248 | 0.64 | KMT2A (0.41) | ELANEALDH1A1MEN1KMT2ACTSG | |
| SCHEMBL16865430 | 0.64 | CYP2C19 (0.58) | ELANEALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6934220 | 0.64 | ALDH1A1 (0.50) | ELANEALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL13297796 | 0.64 | EHMT2 (0.49) | ELANEALDH1A1MEN1KMT2ACTSG | |
| SCHEMBL7587015 | 0.63 | MEN1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |