Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934334 | 0.83 | LMNA (0.40) | ELANEKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6934223 | 0.80 | ELANE (0.44) | ELANEKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6930687 | 0.74 | CA2 (0.36) | KMT2AMEN1ALDH1A1TSHRDDB1 | |
| SCHEMBL6931469 | 0.73 | CA2 (0.35) | KMT2AMEN1ALDH1A1DDB1CRBN | |
| SCHEMBL6931540 | 0.71 | CA2 (0.33) | KMT2AMEN1ALDH1A1DDB1CRBN | |
| SCHEMBL6735933 | 0.67 | HPGD (0.43) | ELANEKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6930362 | 0.67 | ELANE (0.42) | ELANEKMT2AMEN1TSHRF2 | |
| SCHEMBL8489871 | 0.65 | KMT2A (0.40) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7845423 | 0.62 | MEN1 (0.53) | ELANEKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6728248 | 0.62 | KMT2A (0.41) | ELANEKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |