Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930595 | 0.98 | CYP1A2 (0.39) | ADORA2AADORA1CYP1A2PTGS2PTGS1 | |
| Bromide SCHEMBL3129129 | 0.96 | ADORA2A (0.38) | ADORA2AADORA1CYP1A2PTGS2PTGS1 | |
| Perchlorate SCHEMBL3132388 | 0.89 | PTGS2 (0.38) | ADORA2AADORA1CYP1A2PTGS2PTGS1 | |
| SCHEMBL9239435 | 0.83 | CYP1A2 (0.48) | ADORA2AADORA1CYP1A2PTGS2PTGS1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1089067 | 0.81 | PTGS2 (0.39) | ADORA2AADORA1PTGS2PTGS1TP53 | |
| SCHEMBL28926991 | 0.80 | SLC6A4 (0.39) | CYP1A2PTGS2PTGS1IDO1HTR1A | |
| Benzoyl Formic Acid SCHEMBL699656 | 0.80 | CES2 (0.51) | TP53MDM4MDM2SLC6A4SLC6A3 | |
| Iodide SCHEMBL7090862 | 0.80 | ENPP1 (0.43) | PTGS2PTGS1TP53GPR84NPC1 | |
| SCHEMBL3282910 | 0.79 | CYP1A2 (0.50) | ADORA2AADORA1CYP1A2PTGS2PTGS1 | |
| SCHEMBL4669356 | 0.79 | ALDH1A1 (0.41) | ADORA2AADORA1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158363-B1 | Positive resist composition and onium salts of saccharin derivatives | FUJIFILM CORP (JP) | 2014-01-22 | — | — | EP | disclosed |
| EP-1160095-B1 | Heat-sensitive composition and planographic printing plate precursor | FUJIFILM CORP (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-6660446-B2 | Generating acid upon heating | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-6605409-B2 | Includes a compound that generates a specific sulfonimide compound by irradiation with an actinic ray or a radiation and (B) a resin having an acid decomposable group which increases solubility in an alkali developer; improved resolving power | FUJI PHOTO FILM CO., LTD. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020025489-A1 | Generating acid upon heating | FUJIFILM CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| US-20020006578-A1 | Positive resist composition | FUJI PHOTO FILM CO., LTD. | 2002-01-17 | — | — | US | disclosed |
| EP-1160095-A2 | Heat-sensitive composition and planographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1158363-A1 | Positive resist composition and onium salts of saccharin derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |