Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931390 | 1.00 | TSHR (0.36) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8155173 | 0.92 | TSHR (0.33) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8155691 | 0.87 | TSHR (0.33) | TSHRALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL391523 | 0.81 | MGAM (0.41) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL198108 | 0.81 | MGAM (0.41) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL395418 | 0.81 | MGAM (0.41) | TSHRALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL6155363 | 0.79 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPTKDM4EDUSP3 | |
| SCHEMBL6928053 | 0.78 | LMNA (0.36) | TSHRALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL6234988 | 0.78 | LMNA (0.36) | TSHRALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL1406000 | 0.77 | TSHR (0.37) | TSHRALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586616-B1 | Cyanation and esterification of 3,4-epoxybutyric acid sodium salts to form chemical intermediates for antilipemic agents; by-product inhibition | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2003-07-01 | — | — | US | disclosed |
| EP-1149068-A4 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1149068-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | Samsung Fine Chemicals Co., Ltd. (KR) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046186-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO., LTD (KR) | 2000-08-10 | — | — | WO | disclosed |