Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930929 | 0.92 | TSHR (0.36) | TSHRMAPTTDP1L3MBTL1PRKCA | |
| SCHEMBL6931390 | 0.92 | TSHR (0.36) | TSHRMAPTTDP1L3MBTL1PRKCA | |
| SCHEMBL29980213 | 0.83 | MGAM (0.38) | TSHRTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL6400340 | 0.81 | ALDH1A1 (0.35) | L3MBTL1KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL6400336 | 0.80 | LMNA (0.33) | TSHRMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL10087479 | 0.80 | TSHR (0.33) | TSHRMEN1KMT2AGAA | |
| SCHEMBL8155691 | 0.79 | TSHR (0.33) | TSHRMAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL4286159 | 0.78 | NAAA (0.39) | TSHRMAPTL3MBTL1KDM4EDUSP3 | |
| SCHEMBL6053331 | 0.76 | TSHR (0.38) | TSHRMAPTTDP1ALDH1A1GAA | |
| SCHEMBL4909003 | 0.75 | CYP2D6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054860-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIOLS | Warner-Lambert Export Limited (IE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999032434-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIOLS | WARNER-LAMBERT EXPORT LIMITED (IE) | 1999-07-01 | — | — | WO | disclosed |