Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931772 | 0.98 | ALOX15 (0.41) | ALOX15HTTALDH1A1TSHRLTA4H | |
| SCHEMBL6930586 | 0.91 | HRH3 (0.41) | ALOX15TMEM97HRH3TDP1KDM4E | |
| SCHEMBL6927985 | 0.85 | RAB9A (0.43) | ALOX15ALDH1A1CYP1A2CYP3A4LMNA | |
| SCHEMBL25369656 | 0.70 | ALOX15 (0.43) | ALOX15HTTALDH1A1TSHRLTA4H | |
| SCHEMBL22498087 | 0.70 | ALDH1A1 (0.49) | ALOX15HTTALDH1A1TSHRLTA4H | |
| SCHEMBL25366474 | 0.70 | ALOX15 (0.43) | ALOX15HTTALDH1A1TSHRLTA4H | |
| SCHEMBL10725688 | 0.70 | ALDH1A1 (0.49) | ALOX15HTTALDH1A1TSHRLTA4H | |
| Hydrochloric Acid SCHEMBL10728227 | 0.69 | ALDH1A1 (0.47) | ALOX15HTTALDH1A1TSHRCYP1A2 | |
| SCHEMBL25366774 | 0.68 | ALDH1A1 (0.42) | ALOX15HTTALDH1A1TSHRLTA4H | |
| SCHEMBL10728546 | 0.68 | ALDH1A1 (0.50) | ALOX15HTTALDH1A1TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921803-A4 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |
| JP-2000501433-A | — | — | 2000-02-08 | — | — | JP | claimed |
| EP-0921803-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998036752-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 1998-08-27 | — | — | WO | claimed |