SCHEMBL693181

SCHEMBL693181

Cc1cc(=O)n(-c2ccc(P(=O)(O)O)cc2)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.66
ALDH1A1 P00352 6/20 0.66
KMT2A Q03164 5/20 0.66
KDM4E B2RXH2 4/20 0.66
GAA P10253 3/20 0.66
HTT P42858 3/20 0.66
MEN1 O00255 2/20 0.66
SMN1; SMN2 Q16637 3/20 0.60
TDP1 Q9NUW8 1/20 0.60
LMNA P02545 3/20 0.58
RECQL P46063 1/20 0.58
ALKBH3 Q96Q83 1/20 0.41
KDM5A P29375 1/20 0.40
KDM2B Q8NHM5 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
ALKBH5 Q6P6C2 7/20 0.40
ALPL P05186 2/20 0.39
POLB P06746 1/20 0.37
BLM P54132 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL1028813 0.80 MAPT (0.69) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL1266522 0.78 ALKBH5 (0.66) MAPTALDH1A1KMT2AKDM4ESMN1; SMN2
SCHEMBL5203012 0.76 ALDH1A1 (0.69) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL486233 0.76 ALDH1A1 (0.69) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL8592651 0.76 ALDH1A1 (0.69) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL486340 0.76 ALDH1A1 (0.69) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL34121 0.75 ALDH1A1 (0.68) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL395368 0.74 ALDH1A1 (0.66) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL11773403 0.74 MAPT (0.74) MAPTALDH1A1KMT2AKDM4EGAA
SCHEMBL23907023 0.73 MAPT (0.65) MAPTALDH1A1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421613-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP claimed
US-7985266-B2 Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-07-26 US claimed
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof NOXELL CORPORATION 2011-02-17 US claimed
WO-2010123866-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO claimed
EP-2421613-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP disclosed
US-7985266-B2 Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-07-26 US disclosed
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof NOXELL CORPORATION 2011-02-17 US disclosed
WO-2010123866-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof KRT18, LPO, KRTCAP2 MAPT 547/4885ALDH1A1 354/4885KMT2A 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.