Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | IGF2R | P11717 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230688 | 1.00 | LMNA (0.34) | LMNAL3MBTL1SMN1; SMN2NPSR1MGLL | |
| SCHEMBL6932505 | 0.80 | LMNA (0.35) | LMNAL3MBTL1SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL6935659 | 0.80 | LMNA (0.35) | LMNAL3MBTL1SMN1; SMN2NPSR1HTR1A | |
| SCHEMBL8418431 | 0.75 | SRD5A2 (0.38) | LMNAL3MBTL1SMN1; SMN2NPSR1GAA | |
| SCHEMBL6932576 | 0.72 | PPARA (0.35) | LMNAL3MBTL1SMN1; SMN2GAAPTGDR2 | |
| SCHEMBL6932578 | 0.72 | PPARA (0.35) | LMNAL3MBTL1SMN1; SMN2GAAPTGDR2 | |
| SCHEMBL9540468 | 0.71 | LMNA (0.36) | LMNAL3MBTL1SMN1; SMN2NPSR1MGLL | |
| SCHEMBL9540472 | 0.71 | LMNA (0.36) | LMNAL3MBTL1SMN1; SMN2NPSR1MGLL | |
| SCHEMBL6934681 | 0.69 | CXCL12 (0.38) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6934678 | 0.69 | CXCL12 (0.38) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278720-B1 | 1,4-DIARYL-2-FLUORO-4-CYANO-2-BUTENES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES USEFUL THEREFOR | BASF AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| US-20030100789-A1 | Pesticides such as (R,S)-(Z)-1-(1-(p-chlorophenyl)-2-fluoro-4-(4-fluoro-3-phenoxyphenyl)-4 -cyano-2-butenyl)-cyclopropane | HU YULIN (US) | 2003-05-29 | — | — | US | disclosed |
| EP-1278720-A1 | 1,4-DIARYL-2-FLUORO-4-CYANO-2-BUTENES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES USEFUL THEREFOR | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6444838-B2 | CHEMICAL INTERMEDIATES FOR INSECTICIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-20020019556-A1 | Chemical intermediates for insecticides, miticides | INTL PROP DEPT, BASF AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | US | disclosed |
| WO-2001083428-A1 | 1,4-DIARYL-2-FLUORO-4-CYANO-2-BUTENES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES USEFUL THEREFOR | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100789-A1 | Pesticides such as (R,S)-(Z)-1-(1-(p-chlorophenyl)-2-fluoro-4-(4-fluoro-3-phenoxyphenyl)-4 -cyano-2-butenyl)-cyclopropane | DDT, CYP1B1, FAR1 | LMNA 2146/4885L3MBTL1 889/4885SMN1; SMN2 3682/4885 |
| US-20020019556-A1 | Chemical intermediates for insecticides, miticides | DDT, MLYCD, HADHB | LMNA 2658/4885L3MBTL1 1794/4885SMN1; SMN2 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.