Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915707 | 0.75 | L3MBTL1 (0.44) | MAOB | |
| SCHEMBL21268362 | 0.75 | MAPT (0.34) | MAOB | |
| SCHEMBL621805 | 0.74 | GPR3 (0.38) | MAOB | |
| SCHEMBL2452025 | 0.74 | MRGPRX4 (0.41) | RXRARXRBARMMP1MMP2 | |
| SCHEMBL17046408 | 0.73 | L3MBTL1 (0.36) | MAOBCA12CA1CA2CA7 | |
| SCHEMBL4831489 | 0.71 | APP (0.45) | APPRXRARXRBMAOBIDO1 | |
| SCHEMBL3609423 | 0.70 | MAOB (0.46) | MAOBMAOAAR | |
| SCHEMBL220074 | 0.70 | MAPT (0.47) | MAOB | |
| SCHEMBL160011 | 0.70 | GPR3 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6701726 | 0.69 | USP28 (0.49) | APPMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368300-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070462-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |