Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314832 | 0.81 | DNM1 (0.44) | EPHX2PKMDNM1CETPMEN1 | |
| SCHEMBL6932637 | 0.79 | DNM1 (0.43) | EPHX2PKMDNM1CETPMEN1 | |
| SCHEMBL22283488 | 0.76 | CALM1 (0.45) | EPHX2TP53 | |
| SCHEMBL5180297 | 0.74 | SIGMAR1 (0.40) | EPHX2PKMDNM1CETPMEN1 | |
| SCHEMBL9664671 | 0.73 | KCNH2 (0.59) | MEN1KMT2ATP53KCNH2 | |
| SCHEMBL9666364 | 0.73 | KCNH2 (0.59) | MEN1KMT2ATP53KCNH2 | |
| SCHEMBL9645762 | 0.73 | KCNH2 (0.59) | MEN1KMT2ATP53KCNH2 | |
| SCHEMBL9666740 | 0.73 | KCNH2 (0.59) | MEN1KMT2ATP53KCNH2 | |
| SCHEMBL9665763 | 0.73 | KCNH2 (0.59) | MEN1KMT2ATP53KCNH2 | |
| SCHEMBL9666943 | 0.73 | KCNH2 (0.59) | MEN1KMT2ATP53KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831112-B1 | Sheet and tube organosilicon polymers | DOW CORNING (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-0831112-A1 | Sheet and tube organosilicon polymers | DOW CORNING CORPORATION (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5627241-A | Sheet and tube organosilicon polymers | DOW CORNING CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |