Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 3/20 | 0.47 |
| ▸ | USP25 | Q9UHP3 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699108 | 0.86 | USP28 (0.50) | USP28USP25PTGER1KMT2ASMN1; SMN2 | |
| SCHEMBL3774515 | 0.84 | HTT (0.54) | USP28USP25PPARAPTGER1HTT | |
| SCHEMBL6700864 | 0.78 | RXRA (0.51) | USP28USP25PTGER1KDM4ERXRA | |
| SCHEMBL6700568 | 0.73 | MAOB (0.48) | USP28USP25PTGER1HTTRXRA | |
| SCHEMBL6932427 | 0.73 | RXRA (0.42) | PPARAKMT2AKDM4EMEN1RXRA | |
| SCHEMBL6699769 | 0.73 | USP28 (0.47) | USP28USP25PTGER1 | |
| SCHEMBL6696303 | 0.72 | USP28 (0.54) | USP28USP25PTGER1KMT2ASMN1; SMN2 | |
| SCHEMBL6702523 | 0.71 | PTGER1 (0.47) | USP28USP25PPARAPTGER1PPARD | |
| SCHEMBL6701726 | 0.71 | USP28 (0.49) | USP28USP25PTGER1KMT2ASMN1; SMN2 | |
| SCHEMBL16839022 | 0.71 | PPARD (0.46) | PPARAPPARGPPARDMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368300-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070462-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |