Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700568 | 0.89 | MAOB (0.48) | RXRARXRBMRGPRX4PTGER1MAOB | |
| SCHEMBL6702523 | 0.87 | PTGER1 (0.47) | RXRARXRBMRGPRX4PTGER1MAOB | |
| SCHEMBL8337276 | 0.82 | PTGER1 (0.49) | MRGPRX4PTGER1MAOBUSP28USP25 | |
| SCHEMBL6696303 | 0.81 | USP28 (0.54) | MRGPRX4PTGER1MAOBMAOAUSP28 | |
| SCHEMBL2447727 | 0.80 | RXRA (0.63) | RXRARXRBMRGPRX4FOLH1RXRG | |
| SCHEMBL27051378 | 0.80 | TSHR (0.49) | MRGPRX4KDM4EALDH1A1 | |
| SCHEMBL6701726 | 0.79 | USP28 (0.49) | MRGPRX4PTGER1MAOBMAOAUSP28 | |
| SCHEMBL6932748 | 0.78 | USP28 (0.47) | RXRARXRBMRGPRX4PTGER1USP28 | |
| SCHEMBL27051503 | 0.78 | KMT2A (0.48) | RXRARXRBMRGPRX4FOLH1RXRG | |
| SCHEMBL11818371 | 0.78 | PTPRG (0.44) | RXRARXRBMRGPRX4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1368300-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070462-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BCAT2, BCAT1, AADAT | RXRA 2654/4885RXRB 3035/4885MRGPRX4 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.