Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700864 | 0.89 | RXRA (0.51) | MAOBMAOAMRGPRX4PTGER1FFAR4 | |
| SCHEMBL6702523 | 0.88 | PTGER1 (0.47) | MAOBMAOAMRGPRX4SMPD1PTGER1 | |
| SCHEMBL8337276 | 0.80 | PTGER1 (0.49) | MAOBMRGPRX4PTGER1LRRK2USP28 | |
| SCHEMBL13581056 | 0.79 | MRGPRX4 (0.55) | MRGPRX4LRRK2 | |
| SCHEMBL13581072 | 0.79 | EPHX2 (0.50) | MRGPRX4FFAR4RXRARXRB | |
| SCHEMBL5927325 | 0.78 | PTGER1 (0.51) | SMPD1PTGER1LRRK2CCR5RXRA | |
| SCHEMBL6699108 | 0.78 | USP28 (0.50) | MRGPRX4SMPD1PTGER1USP28USP25 | |
| SCHEMBL6696303 | 0.78 | USP28 (0.54) | MAOBMAOAMRGPRX4PTGER1USP28 | |
| SCHEMBL5431545 | 0.77 | LRRK2 (0.63) | SMPD1LRRK2CCR5ALDH1A1 | |
| SCHEMBL2888586 | 0.77 | MAPT (0.49) | MAOBMAOASMPD1FFAR4CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176446-A1 | Substituted amino dicarboxylic acid derivatives | BCAT2, BCAT1, AADAT | MAOB 2990/4885MAOA 2728/4885MRGPRX4 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.