SCHEMBL6933217

SCHEMBL6933217

CC1(C)CC(Nc2ccccc2)CC(C)(C)N1[O]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
PKM P14618 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
RAD52 P43351 1/20 0.53
GFER P55789 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
CA9 Q16790 5/20 0.43
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
CCR5 P51681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9002784 0.84 ALDH1A1 (0.54) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL6933221 0.82 KMT2A (0.53) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL19780860 0.78 MAPT (0.65) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL6933594 0.75 KDM4E (0.48) KMT2AALDH1A1MEN1LMNACA1
SCHEMBL9380274 0.74 KMT2A (0.87) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL25816391 0.70 MEN1 (0.51) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL809441 0.70 ALDH1A1 (0.69) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL8738952 0.69 ALDH1A1 (1.00) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL17980498 0.69 ALDH1A1 (0.49) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL6753444 0.68 MAPT (0.52) KMT2AMEN1MAPTSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660181-B2 Inhibiting the premature polymerization of ethylenically unsaturated monomers by adding mixture comprising a first inhibitor comprising 4-amino-2,2,6,6-tetramethylpiperidinyloxy and other inhibitor CROMPTON CORPORATION 2003-12-09 US disclosed
US-20030080318-A1 Inhibition of polymerization of unsaturated monomers ADDIVANT USA, LLC 2003-05-01 US disclosed