SCHEMBL6933221

SCHEMBL6933221

CC1(C)CC(Nc2ccccc2)CC(C)(C)N1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ALDH1A1 P00352 2/20 0.53
ALOX15 P16050 2/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
PKM P14618 1/20 0.53
ALOX12 P18054 1/20 0.53
RAD52 P43351 1/20 0.53
GFER P55789 1/20 0.53
GAA P10253 4/20 0.47
KDM4E B2RXH2 2/20 0.47
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
CCR5 P51681 1/20 0.38
HTT P42858 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9002784 0.84 ALDH1A1 (0.54) KMT2AMAPTL3MBTL1ALDH1A1ALOX15
SCHEMBL6933217 0.82 KMT2A (0.53) KMT2AMAPTL3MBTL1ALDH1A1ALOX15
SCHEMBL19780860 0.78 MAPT (0.65) KMT2AMAPTL3MBTL1ALDH1A1ALOX15
SCHEMBL4399645 0.78 CA1 (0.41) KMT2AMAPTL3MBTL1ALDH1A1ALOX15
SCHEMBL6933598 0.75 ACHE (0.46) KMT2AALDH1A1MEN1LMNAGAA
SCHEMBL9380274 0.74 KMT2A (0.87) KMT2AMAPTL3MBTL1ALDH1A1ALOX15
SCHEMBL3916706 0.73 KDM4E (0.72) KMT2AL3MBTL1MEN1GAAKDM4E
SCHEMBL4349095 0.72 TRPA1 (0.47) KMT2AMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL9901441 0.72 P2RX7 (0.43) KMT2AMAPTALDH1A1MEN1GAA
SCHEMBL18374827 0.71 GAA (0.64) KMT2AMAPTALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660181-B2 Inhibiting the premature polymerization of ethylenically unsaturated monomers by adding mixture comprising a first inhibitor comprising 4-amino-2,2,6,6-tetramethylpiperidinyloxy and other inhibitor CROMPTON CORPORATION 2003-12-09 US disclosed
US-20030080318-A1 Inhibition of polymerization of unsaturated monomers ADDIVANT USA, LLC 2003-05-01 US disclosed