Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 6/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931449 | 0.85 | ALDH1A1 (0.39) | PTGS1TPH1TACR1GAAALPI | |
| Phenylalanine SCHEMBL7906184 | 0.82 | SLC7A5 (0.52) | PTGS1TPH1ACEALPIPKM | |
| SCHEMBL6368433 | 0.82 | PTGS1 (0.51) | PTGS1LTA4HPTGS2TPH1KDM4A | |
| SCHEMBL6429072 | 0.82 | PTGS1 (0.51) | PTGS1LTA4HPTGS2TPH1KDM4A | |
| SCHEMBL7905125 | 0.81 | ITGB1 (0.43) | PTGS1PTGS2TPH1ACEALPI | |
| SCHEMBL6935180 | 0.81 | DPP4 (0.47) | PTGS1LTA4HACEALPIPKM | |
| SCHEMBL7904116 | 0.81 | SLC7A5 (0.45) | PTGS1TPH1ACEALPIPKM | |
| SCHEMBL6931447 | 0.81 | CTSL (0.40) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL6934867 | 0.80 | LTA4H (0.39) | LTA4HTPH1 | |
| SCHEMBL6936891 | 0.80 | S1PR5 (0.47) | PTGS1TPH1ACEALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984981-B1 | ANTI-INFLAMMATORY TYROSINE DERIVATIVES | CELLTECH THERAPEUTICS LTD (GB) | 2003-12-17 | — | — | EP | disclosed |
| US-6093696-A | N-ACETYL-D-THIOPROLINE-(O-2,6-DICHLOROBENZYL)-L-TYROSINE, FOR EXAMPLE; SELECTIVELY INHIBIT THE ALPHA 4 SUBGROUP OF INTEGRINS FROM BINDING TO THEIR LIGANDS; USE IN PROPHYLAXIS OR TREATMENT OF IMMUNE OR INFLAMMATORY DISEASES | CELLTECH THERAPEUTICS, LIMITED (GB) | 2000-07-25 | — | — | US | disclosed |