Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.65 |
| ▸ | CTSK | P43235 | 8/20 | 0.65 |
| ▸ | REN | P00797 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 5/20 | 0.60 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862861 | 0.94 | CTSK (0.72) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL10880715 | 0.92 | REN (0.70) | CTSKRENCTSLCTSSCTSB | |
| SCHEMBL15255353 | 0.91 | REN (0.66) | CAPN1CTSKRENCTSLCTSS | |
| SCHEMBL9551300 | 0.91 | REN (0.66) | CAPN1CTSKRENCTSLCTSS | |
| SCHEMBL9551248 | 0.90 | REN (0.68) | CAPN1CTSKRENCTSLHTRA1 | |
| SCHEMBL1980963 | 0.90 | CTSK (0.76) | CAPN1CTSKRENCTSLCTSS | |
| SCHEMBL1980967 | 0.90 | CTSK (0.76) | CAPN1CTSKRENCTSLCTSS | |
| SCHEMBL10349214 | 0.89 | CTSK (0.69) | CAPN1CTSKRENCTSLHTRA1 | |
| SCHEMBL7607055 | 0.89 | CTSK (0.69) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL30645061 | 0.89 | CTSL (0.61) | CAPN1CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649414-B1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | ARDENT PHARMACEUTICALS INC (US) | 2003-04-16 | — | — | EP | disclosed |
| US-5854249-A | Opioid diarylmethylpiperazines and piperidines | DELTA PHARMACEUTICALS, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5658908-A | RECEPTOR BINDING SPECIES FOR MEDIATING ANALGESIA, COMBATTING DRUG ADDICTION, DRUG OVERDOSE | DELTA PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0649414-A1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993015062-A1 | OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| EP-0073829-B1 | RAPID, QUANTITATIVE PEPTIDE SYNTHESIS USING MIXED ANHYDRIDES | BIORESEARCH INC. (US) | 1986-01-29 | — | — | EP | disclosed |
| EP-0073829-A4 | RAPID, QUANTITATIVE PEPTIDE SYNTHESIS USING MIXED ANHYDRIDES. | BIORES INC (US) | 1983-11-09 | — | — | EP | disclosed |
| EP-0073829-A1 | RAPID, QUANTITATIVE PEPTIDE SYNTHESIS USING MIXED ANHYDRIDES. | BIORESEARCH INC (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4351762-A | Rapid, quantitative peptide synthesis using mixed anhydrides | BIORESEARCH, INC. (US) | 1982-09-28 | — | — | US | disclosed |
| WO-1982003078-A1 | RAPID,QUANTITATIVE PEPTIDE SYNTHESIS USING MIXED ANHYDRIDES | BIORESEARCH INC (US) | 1982-09-16 | — | — | WO | disclosed |