Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMURF1 | Q9HCE7 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818254 | 0.79 | SERPINE1 (0.57) | SMURF1MAPTKDM4EAKR1C3 | |
| SCHEMBL6818811 | 0.74 | AKR1C2 (0.48) | MAPTMEN1KMT2AAKR1C3POLB | |
| SCHEMBL4076415 | 0.74 | PTPN1 (0.67) | SMURF1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27287798 | 0.72 | POLB (0.59) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL6822210 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2ADUSP3PTPN1POLB | |
| SCHEMBL10743840 | 0.72 | KMT2A (0.64) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL768632 | 0.70 | PTPN1 (0.56) | MAPTKDM4EMEN1KMT2ADUSP3 | |
| SCHEMBL12000495 | 0.69 | PTGS1 (0.60) | MAPTKDM4EDUSP3PTPN1SMN1; SMN2 | |
| SCHEMBL21932440 | 0.69 | PTPN1 (0.54) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL4337496 | 0.69 | DUSP3 (0.56) | SMURF1DUSP3PTPN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | SMURF1 712/4885MAPT 4759/4885KDM4E 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.