Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMURF1 | Q9HCE7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818811 | 0.87 | AKR1C2 (0.48) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL6822210 | 0.84 | ALDH1A1 (0.43) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL6933414 | 0.79 | SMURF1 (0.49) | KDM4EAKR1C3MAPTSMURF1 | |
| SCHEMBL6818030 | 0.78 | MEN1 (0.66) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4076415 | 0.73 | PTPN1 (0.67) | KDM4EHSD17B10MAPTSMURF1 | |
| SCHEMBL421010 | 0.73 | SERPINE1 (1.00) | SERPINE1KDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL418103 | 0.73 | SERPINE1 (0.71) | SERPINE1KDM4EHSD17B10AKR1C4AKR1C3 | |
| SCHEMBL4337496 | 0.73 | DUSP3 (0.56) | SMURF1 | |
| SCHEMBL7089912 | 0.73 | KCNMA1 (0.68) | SERPINE1KDM4EHSD17B10AKR1C4AKR1C3 | |
| SCHEMBL27851450 | 0.73 | SERPINE1 (0.70) | SERPINE1KDM4EHSD17B10AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | SERPINE1 1860/4885KDM4E 1240/4885HSD17B10 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.