Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059109 | 0.84 | PIK3CA (0.49) | ABL1 | |
| SCHEMBL23139485 | 0.84 | MAPK1 (0.43) | ABL1MAPK1 | |
| SCHEMBL26578135 | 0.81 | MAPK1 (0.41) | ABL1MAPK1 | |
| SCHEMBL24703391 | 0.80 | PIK3CA (0.54) | ABL1MAPK1 | |
| SCHEMBL16204330 | 0.74 | — | — | |
| SCHEMBL19416867 | 0.74 | RAB9A (0.62) | MAPK1 | |
| SCHEMBL14506671 | 0.74 | PIK3CA (0.75) | MAPK1 | |
| SCHEMBL6933717 | 0.73 | JUN (0.41) | ABL1MAPK1 | |
| SCHEMBL2551574 | 0.73 | ABL1 (0.55) | ABL1MAPK1 | |
| SCHEMBL23139486 | 0.71 | MAPK1 (0.45) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114275-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2011-09-22 | — | — | WO | disclosed |